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. 2018 Oct 22;7(10):179. doi: 10.3390/cells7100179

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Exosomes containing aquaporins (AQPs) have been used to develop novel biomedical tools. As the abundance of AQPs in exosomes is modified under a specific disorder, they can be used as new biomarkers in the diagnosis of different diseases. Exosomes could also be used as drug delivery systems as they are able to cross biological barriers and guarantee the stability and bioavailability of drugs. One of the biological functions of exosomes is the delivery of RNA, based on which exosomes are used to transport siRNA used in therapies.