Table 7.
Effects of oral administration of Plukenetia conophora and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methylon malondialdehyde and nitric oxide levels of male Wistar rats treated with a single IP dose of 2 mg/kg of cadmium chloride.
| Group | Testis | Epididymis | ||
|---|---|---|---|---|
| MDA | NO | MDA | NO | |
| Control | 4.36±0.98 | 2.50±0.33 | 4.91±1.38 | 3.13±0.16 |
| Cadmium chloride | 29.37±3.58+ | 4.04±0.62+ | 18.91±2.52+ | 3.92±0.02 |
| Cd+Vit E | 9.24±0.70** | 2.79±0.00* | 6.74±0.22** | 3.00±0.17* |
| Cd+100 mg/kg PC | 6.41±0.88** | 2.42±0.07* | 6.06±0.68** | 3.07±0.56 |
| Cd+200mg/kg PC | 5.34±1.32** | 2.43±0.09* | 4.51±0.15** | 2.66±0.22* |
| Cd+25 mg/kg DDMP | 10.93±1.82** | 2.07±0.07* | 9.51±1.63** | 3.20±0.28 |
| Cd+50 mg/kg DDMP | 4.63±1.12** | 2.83±0.24* | 2.47±0.16** | 3.11±0.00 |
Values are represented in mean values±SEM, n=6
+
P<0.05 when compared with controls
*
p<0.05 when compared with the group given cadmium chloride alone
**
p<0.01 when compared with the group given cadmium chloride alone
MDA - Malondialdehyde
NO - Nitric oxide
PC – Plukenetia conophora
DDMP - 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl