Table 1.

Downstream target genes of Nrf-2, NF-κB and AR.

Downstream Target Genes
Nrf-2	NAD(P)H:quinone oxidoreductase-1 (NQO-1), heme-oxygenase-1 (HO-1), glutathione S-transferaseA2 (GSTA2), γ-glutamylcysteine synthetase (GCS), epoxide hydrolase, leukotriene B4 dehydrogenase, aflatoxin B1 dehydrogenase, ferritin and UDP-glucuronosyltransferase (UGT) 1A1
NF-κB	Caspase-8 inhibitor FLIP, the inhibitor of apoptosis proteins c-IAP1/2 and XIAP, B-cell lymphoma 2 (Bcl-2), Bcl-extralarge (Bcl-xL), Bax (bcl-2-like protein 4), vascular-endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), IL-8, matrix metalloproteinase-9 (MMP-9), selectins and integrins
AR	Prostate specific antigen (PSA), fibroblast growth factor 8 (FGF8), cyclin dependent kinase 1 (Cdk1), Cdk2, prostate transmembrane protein androgen induced 1 (PMEPA1), transmembrane serine protease 2 (TMPRSS2) and FK506 binding protein 5 (FKBP5)