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. 2018 Sep 26;7(10):151. doi: 10.3390/cells7100151

Figure 1.

Figure 1

dHUWE1 is required for salivary gland development. (A) Schematic diagram of human and Drosophila dHUWE1 proteins (not to scale). UBA (green) and WWE (yellow) are ubiquitin-binding motifs. BH3; Bcl2-homology domain, and HECT domain is the catalytic core (red). (B–D”) Indirect immunofluorescence confocal microscopy images of wild-type and the indicated transgenic lines stained with anti-dHUWE1 antibody (red). DAPI (blue) marks DNA, and the scale bar is 50 μm. (B) Endogenous levels of dHUWE1. (C–D”) Expression of UAS-dHUWE1-RNAi (C,C”) or UAS-dHUWE1 (D,D”) under the control of ptc-Gal4.