Table 1.
Peroxiredoxin expression and associations with radiosensitivity and prognosis of colorectal cancer.
| Gene Name | Expression in CRC | Radiosensitivity | Prognostic Indicator | Predictor of Pathological Tumor Response | Reference(s) |
|---|---|---|---|---|---|
| PRDX1 | ↑ | ↑ expression → ↓ radiosensitivity |
Yes | ↑ expression → ↓ response |
[47] |
| PRDX2 | ↑ | ↓ expression → ↑ radiosensitivity |
Yes | - | [48,49,50,51,52,53] |
| PRDX3 | ↑ | - | - | - | [54] |
| PRDX4 | ↑ / ↓ | - | Yes | Yes | [46,55,56] |
| PRDX5 | ↑ | - | - | - | [57] |
| PRDX6 | ↑ | - | - | - | [46] |
Legend: ↑ = increased, ↓ = decreased, → = association between expression and radiosensitivity or tumor response. CRC: colorectal cancer. PRDX: peroxiredoxin gene.