TABLE 2.

Comparison of the relative inhibitory actions of acyl-PAF, lyso-PC, and lyso-PAF on alkyl-PAF-induced death in Swiss albino mice

Group	First Injection	Second Injection	Deaths/Total	Survival (%)
1	Vehicle (PBS containing 0.1% HSA)	—	0/6	100
2	Alkyl-PAF (250 μg/kg)	—	6/6 (all died between 15 and 20 min)	0
3	Acyl-PAF (12.5 mg/kg)	Alkyl-PAF (250 μg/kg)	0/6	100
4	Lyso-PC (12.5 mg/kg)	Alkyl-PAF (250 μg/kg)	6/6 (1 died within 20 min; 2 died between 15 and 16 h; 1 died between 20 and 21 h; and 2 died between 40 and 43 h)	0
5	Lyso-PAF (12.5 mg/kg)	Alkyl-PAF (250 μg/kg)	3/6 (1 died between 15 and 16 h; 1 died between 30 and 36 h; and 1 died between 40 and 41 h)	50

Swiss albino mice weighing between 20 and 25 g were assigned into 5 groups, each of which contained 6 mice. Mice were injected with acyl-PAF or lyso-PC or lyso-PAF (12.5 mg/kg) in a final volume of 0.5 ml PBS containing 0.1% HSA 3 h prior to injecting a lethal dose of alkyl-PAF (250 μg/kg). Control mice received the vehicle used in the preparation of acyl-PAF or lyso-PAF or lyso-PC (0.5 ml PBS containing 0.1% albumin). Survival was monitored for up to 6 days.