Fig. 1.
Chromatographic profiles for apoE mimetic peptides. HPLC profiles for Ac-hE18A-NH2, Ac-[R]hE18A-NH2, Ac-Aha-[R]hE18A-NH2, Oct-[R]hE18A-NH2, Myr-hE18A-NH2, and Myr-[R]hE18A-NH2. Peptides were injected on a C-18 reverse-phase column and eluted using an acetonitrile-water gradient (35% to 70%). UV absorbance was monitored at 220 nm (A). B: Plot of acyl chain length versus log retention time for Ac-[R]hE18A-NH2, Ac-Aha-[R]hE18A-NH2, Oct-[R]hE18A-NH2, and Myr-[R]hE18A-NH2.