Table 4.
Performance of the serum biomarker panel miR-196b + TIMP1 + LCN2.
| Comparison | p | AUC (95% CI) | Sensitivity at 95% Specificity | Specificity at 95% Sensitivity |
|---|---|---|---|---|
| PDAC vs. Healthy control | 0.0012 | 0.93 (0.8162 to 1.044) | 80% | 80% |
| FPC vs. Healthy control | 0.0004 | 0.97 (0.9071 to 1.033) | 80% | 80% |
| Significant lesions and stage I PDAC vs. healthy controls | 0.029 | 1 (1.000 to 1.000) | 100% | 100% |
| PDAC vs. chronic pancreatitis | 0.0025 | 0.9 (0.7559 to 1.044) | 50% | 80% |
| FPC vs. chronic pancreatitis | 0.0007 | 0.95 (0.8622 to 1.038) | 80% | 80% |
PDAC, pancreatic ductal adenocarcinoma, FPC, familial pancreatic cancer, AUC, area under curve, CI, confidence interval.