Table 3.
Differences in DRD4 and NEO Five Factor Inventory between healthy control subjects and addicted subjects.
| NEO Five Factor Inventory | DRD4 Ex3 | Main Effects ANOVA | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Addicted Subjects (n = 299) | Control (n = 301) | s/s (n = 365) | s/l (n = 197) | l/l (n = 36) | Full Model | Main Effects | |||
| F (p Value) | Factor | F (p Value) | η2 | ||||||
| Neuroticism/scale | M 6.73 SD 2.18 |
M 4.67 SD 2.01 |
M 5.77 SD 2.27 |
M 5.71 SD 2.27 |
M 4.81 SD 2.01 |
F3,595 = 48.75
p = 0.000000 R2 = 0.197 |
intercept | F1,595 = 1768.22 (p = 0.000000) | 0.748 |
| addicted/control | F1,595 = 139.30 (p = 0.000000) | 0.190 | |||||||
| DRD4 Ex3 | F2,595 = 0.84 (p = 0.433326) | 0.003 | |||||||
| Extraversion/scale | M 5.76 SD 2.14 |
M 6.37 SD 1.98 |
M 6.08 SD 2.03 |
M 5.89 SD 2.15 |
M 6.89 SD 2.07 |
F3,595 = 6.31
p = 0.000321 R2 = 0.031 |
intercept | F1,595 = 2328.11 (p = 0.000000) | 0.796 |
| addicted/control | F1,595 = 11.73 (p = 0.000657) | 0.019 | |||||||
| DRD4 Ex3 | F2,595 = 2.76 (p = 0.063836) | 0.009 | |||||||
| Openness/scale | M 5.01 SD 2.02 |
M 4.53 SD 1.61 |
M 4.66 SD 1.81 |
M 4.94 SD 1.88 |
M 4.97 SD 1.90 |
F3,595 = 4.87
p = 0.002353 R2 = 0.024 |
intercept | F1,595 = 1804.89 (p = 0.000000) | 0.752 |
| addicted/control | F1,595 = 11.14 (p = 0.000897) | 0.018 | |||||||
| DRD4 Ex3 | F2,595 = 2.15 (p = 0.117517) | 0.007 | |||||||
| Agreeability/scale | M 4.30 SD 1.93 |
M 5.59 SD 2.09 |
M 4.90 SD 2.16 |
M 5.09 SD 2.01 |
M 4.75 SD 2.21 |
F3,595 = 21.95
p = 0.000000 R2 = 0.100 |
intercept | F1,595 = 1446.57 (p = 0.000000) | 0.709 |
| addicted/control | F1,595 = 64.36 (p = 0.000000) | 0.098 | |||||||
| DRD4 Ex3 | F2,595 = 1.57 (p = 0.209316) | 0.005 | |||||||
| Conscientiousness/scale | M 5.59 SD 2.27 |
M 6.08 SD 2.15 |
M 5.80 SD 2.25 |
M 5.79 SD 2.19 |
M 6.44 SD 2.03 |
F3,595 = 3.14 p = 0.024785 R2 = 0.016 |
intercept | F1,595 = 1832.62 (p = 0.000000) | 0.755 |
| addicted/control | F1,595 = 6.52 (p = 0.010937) | 0.011 | |||||||
| DRD4 Ex3 | F2,595 = 1.004 (p = 0.366928) | 0.003 | |||||||
Bonferroni correction was used, and the p value was reduced to 0.01 (p = 0.05/5 (number of statistical tests conducted)). M—mean, SD—standard deviation. Significances between-group differences are marked in bold.