Table 1.
An overview of the acute and chronic toxicities.
| Characteristic | Acute Toxicity, No. (%) | Chronic Toxicity, No. (%) | ||||
|---|---|---|---|---|---|---|
| (n = 15) | C12 Alone (n = 7) |
IMRT + C12 (n = 8) |
Total (n = 15) |
C12 Alone (n = 7) |
IMRT + C12 (n = 8) |
Total (n = 15) |
| overall toxicity | ||||||
| grade 1 | 3 (43) | 2 (25) | 5 (33) | 2 (29) | 3 (38) | 5 (33) |
| grade 2 | 2 (29) | 4 (50) | 6 (40) | 2 (29) | 1 (13) | 3 (20) |
| grade 3 | 2 (29) | 2 (25) | 4 (27) | 1 (14) | 0 | 1 (7) |
| grade 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| dysphagia | ||||||
| grade 1 | 3 (43) | 3 (38) | 6 (40) | 3 (43) | 0 | n = 3 (20) |
| grade 2 | 1 (14) | 2 (25) | 3 (20) | 1 (14) | 0 | n = 1 (7) |
| grade 3 | 1 (14) | 1 (13) | 2 (13) | 0 | 0 | 0 |
| odynophagia | ||||||
| grade 1 | 4 (57) | 3 (38) | 7 (53) | 0 | 0 | 0 |
| grade 2 | 1 (14) | 1 (13) | 2 (13) | 0 | 0 | 0 |
| grade 3 | 2 (29) | 1 (13) | 3 (20) | 0 | 0 | 0 |
| mucositis | ||||||
| grade 1 | 2 (29) | 0 | 2 (13) | 0 | 0 | 0 |
| grade 2 | 1 (14) | 3 (38) | 2 (13) | 0 | 0 | 0 |
| dermatitis | ||||||
| grade 1 | 3 (43) | 3 38 () | 6 (40) | 0 | 0 | 0 |
| grade 2 | 0 | 3 (38) | 3 (20) | 0 | 0 | 0 |
| xerostomia | ||||||
| grade 1 | 3 (43) | 4 (50) | 7 (53) | 5 (71) | 3 (38) | 8 (53) |
| grade 2 | 1 (14) | 0 | 1 (7) | 0 | 3 (38) | 3 (20) |
| hoarseness | ||||||
| grade 1 | 2 (29) | 3 (38) | 5 (33) | 2 (29) | 3 (38) | 5 (33) |
| grade 2 | 2 (29) | 1 (13) | 3 (20) | 2 (29) | 1 (13) | 3 (20) |
| grade 3 | 0 | 0 | 0 | 1 (14) | 0 | 1 (7) |
| fatigue | ||||||
| grade 1 | 0 | 2 (25) | 2 (13) | 2 (29) | 1 (13) | 3 (20) |
| grade 2 | 4 (57) | 0 | 4 (27) | 1 (14) | 0 | 1 (7) |
| grade 3 | 0 | 1 (13) | 1 (7) | 0 | 0 | 0 |
| dysgeusia | ||||||
| grade 1 | 0 | 2 (25) | 2 (13) | 1 (14) | 1 (13) | 2 (13) |
| grade 2 | 0 | 2 (25) | 2 (13) | 0 | 0 | 0 |
| alopecia | ||||||
| grade 1 | 3 (43) | 2 (25) | 5 (33) | 0 | 0 | 0 |
| dry cough | ||||||
| grade 1 | 1 (14) | 1 (13) | 2 (13) | 0 | 0 | 0 |
Abbreviations: C12 = carbon ions, IMRT = intensity-modulated RT.