Skip to main content
. 2018 Oct 22;9(10):514. doi: 10.3390/genes9100514

Figure 1.

Figure 1

Occurrence of cytochrome P450 2C9 (CYP2C9), cytochrome P450 2D6 (CYP2D6) and cytochrome P450 oxidoreductase (CYPOR) missense variants in the Pakistani cohort vs. eleven world populations represented in the 1000 Genomes Project. The p-value of the χ2 test in CYP2C9, CYP2D6 and CYPOR missense variants among the Pakistani cohort vs. global populations were calculated using the chi-square test and values were considered significant at the p < 0.05 level. Statistically significant variations are represented by a blue bar (a–f). Global populations are arranged according to the least significant to most significant negative log(p-value). Populations included were African ancestry in Southwest USA (ASW); Luhya in Webuye, Kenya (LWK); Yoruba in Ibadan, Nigeria (YRI); Mexican ancestry in Los Angeles, CA, USA (MEX); Han Chinese in Beijing, China (CHB); Southern Han Chinese, China (CHS); Japanese in Tokyo, Japan (JPT); Utah, USA residents with Northern and Western European ancestry from the Centre d’Etude du Polymorphisme Humain (CEPH) collection (CEU); Toscani in Italy (TSI); Gujarati Indians in Houston, Texas, USA (GIH); Sri Lankan Tamal in UK (STU). Numbers in parentheses indicate the group size.