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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Proc IEEE Int Symp Bioinformatics Bioeng. 2018 Jan 11;2017:568–573. doi: 10.1109/BIBE.2017.00014

Table III.

Prediction performance of the models, a) data, b) with downsampling, c) with SMOTE. LR: logistic regression, GAM: generalized additive model, RF: random forests, SVM: support vector machine, NN: neural network, XGB: extreme gradient boosting, NB: Naïve Bayes. AUC: Area under the ROC Curve. CI: Confidence interval.

a)
Model Accuracy (CI 0.05, 0.95) AUC (CI 0.05, 0.95) Sensitivity (CI 0.05, 0.95) Specificity (CI 0.05, 0.95)
LR 0.77 (0.68,0.83) 0.86 (0.85,0.87) 0.78 (0.70,0.88) 0.77 (0.67,0.83)
GAM 0.81 (0.76,0.83) 0.86 (0.84,0.88) 0.75 (0.69,0.83) 0.81 (0.76,0.83)
RF 0.80 (0.75,0.87) 0.85 (0.83,0.86) 0.81 (0.75,0.88) 0.73 (0.58,0.80)
SVM 0.84 (0.71,0.89) 0.71 (0.62,0.75) 0.48 (0.31,0.62) 0.85 (0.72,0.91)
NN 0.57 (0.48,0.71) 0.85 (0.83,0.87) 0.56 (0.47,0.70) 0.90 (0.81,0.95)
XGB 0.73 (0.49,0.77) 0.85 (0.84,0.86) 0.73 (0.47,0.77) 0.82 (0.76,0.96)
NB 0.75 (0.65,0.77) 0.79 (0.77,0.82) 0.71 (0.66,0.81) 0.75 (0.64,0.77)
b)
Model Accuracy (CI 0.05, 0.95) AUC (CI 0.05, 0.95) Sensitivity (CI 0.05, 0.95) Specificity (CI 0.05, 0.95)
LR 0.81 (0.72,0.83) 0.86 (0.84,0.87) 0.74 (0.67,0.85) 0.82 (0.72,0.84)
GAM 0.74 (0.72,0.75) 0.86 (0.84,0.87) 0.82 (0.79,0.86) 0.73 (0.72,0.75)
RF 0.78 (0.76,0.80) 0.86 (0.84,0.87) 0.78 (0.75,0.80) 0.76 (0.70,0.81)
SVM 0.73 (0.69,0.77) 0.85 (0.83,0.87) 0.82 (0.76,0.89) 0.71 (0.69,0.77)
NN 0.86 (0.03,0.92) 0.85 (0.83,0.87) 0.87 (0,0.94) 0.60 (0.39,1)
XGB 0.64 (0.60,0.75) 0.85 (0.83,0.86) 0.63 (0.59,0.75) 0.88 (0.79,0.92)
NB 0.68 (0.66,0.71) 0.79 (0.77,0.81) 0.79 (0.74,0.84) 0.68 (0.65,0.71)
c)
Model Accuracy (CI 0.05, 0.95) AUC (CI 0.05, 0.95) Sensitivity (CI 0.05, 0.95) Specificity (CI 0.05, 0.95)
LR 0.75 (0.73, 0.81) 0.85 (0.83, 0.86) 0.80 (0.70, 0.85) 0.75 (0.72, 0.81)
GAM 0.69 (0.62, 0.74) 0.85 (0.84, 0.87) 0.86 (0.81, 0.91) 0.68 (0.61, 0.74)
RF 0.81 (0.68, 0.89) 0.85 (0.84, 0.87) 0.81 (0.67, 0.90) 0.73 (0.56, 0.85)
SVM 0.70 (0.65,0.74) 0.84 (0.82,0.87) 0.84 (0.77,0.90) 0.69 (0.66,0.75)
NN 0.46 (0.03, 0.76) 0.84 (0.75, 0.86) 0.97 (0.77, 1) 0.44 (0, 0.76)
XGB 0.60 (0.10, 0.71) 0.84 (0.81, 0.85) 0.59 (0.07, 0.71) 0.90 (0.79, 1)
NB 0.79 (0.78, 0.90) 0.80 (0.77, 0.81) 0.75 (0.68, 0.79) 0.71 (0.70, 0.76)