Figure 2.

The influence of BCL6 on the proliferation capacity, cell cycle progression, and cell apoptosis rate of glioblastoma cells. (a) CCK8 assay detected that cell proliferation vitality was inhibited in glioblastoma cells after BCL6 knockdown in U87 and U251 cells. (b) The result of clone formation assay showed that cell proliferation capacity was reduced after BCL6 knockdown U87 and U251 cells. Relative expression was calculated with respect to the control group without treatment. ((c) and (d)) The result of flow cytometry analysis of cell cycle and apoptosis in U87 and U251 cells transfected with shBCL6 or scramble sequences (∗∗ p<0.01; ∗ p<0.05).