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. 2018 Jul 20;187(11):2449–2459. doi: 10.1093/aje/kwy149

Table 4.

Effects of the Intervention on the Risk of Ever Reporting Drug-Injection–Related Risk Behavior by 30 Months After Baseline Among Participants in the HIV Prevention Trials Network 037 Study (n = 651), Philadelphia, Pennsylvania, 2002–2006

Effect Stratified Models Aggregate Models
Unadjusted Adjusteda Unadjusted Adjusteda Unadjusted Adjusteda Unadjusted Adjusteda
RDb 95% CI RDb 95% CI RR 95% CI RR 95% CI RDb 95% CI RDb 95% CI RR 95% CI RR 95% CI
Any shared “works”
 Individual −5 −16, 7 −7 −20, 5 0.65 0.28, 1.51 0.47 0.18, 1.21 −5 −16, 6 −8 −19, 3 0.65 0.28, 1.47 0.52 0.23, 1.15
 Disseminated −6 −14, 1 −5 −13, 2 0.69 0.42, 1.13 0.75 0.45, 1.25 −6 −14, 1 −5 −13, 3 0.69 0.42, 1.14 0.76 0.46, 1.25
 Composite −11 −20, −2 −13 −22, −3 0.45 0.22, 0.89 0.35 0.16, 0.78 −11 −20, −2 −13 −22, −4 0.45 0.22, 0.89 0.39 0.20, 0.78
 Overall −8 −14, −2 −8 −14, −2 0.60 0.39, 0.92 0.61 0.39, 0.94 −8 −14, −2 −8 −14, −2 0.60 0.39, 0.92 0.61 0.39, 0.94
Any risk behaviorc
 Individual 2 −14, 18 0 −18, 17 1.07 0.73, 1.56 0.99 0.68, 1.45 2 −13, 18 0 −16, 15 1.07 0.76, 1.53 0.97 0.68, 1.39
 Disseminated −8 −18, 2 −5 −16, 5 0.83 0.64, 1.07 0.88 0.69, 1.13 −8 −18, 2 −7 −17, 4 0.83 0.64, 1.06 0.85 0.66, 1.10
 Composite −5 −18, 7 −6 −20, 8 0.89 0.67, 1.18 0.88 0.66, 1.16 −5 −18, 7 −7 −20, 6 0.89 0.67, 1.18 0.83 0.62, 1.10
 Overall −7 −15, 1 −7 −16, 2 0.85 0.69, 1.04 0.85 0.69, 1.04 −7 −15, 1 −7 −16, 2 0.85 0.69, 1.04 0.85 0.69, 1.04

Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus; RD, risk difference; RR, risk ratio.

a Adjusted for sex (male vs. female), age (years), marital status (single vs. not single), education (high school or more vs. not completing high school), and employment (unemployed vs. employed) and for time-varying covariates set to their baseline values: “crack” cocaine use (yes vs. no), powdered cocaine use (yes vs. no), benzodiazepine use (yes vs. no), heroin use (yes vs. no), participation in a drug treatment program in the past 6 months (yes vs. no), spent the night on the street in the past 6 months (yes vs. no), spent time in jail in the past 6 months (yes vs. no), frequency of excessive alcohol use (getting drunk vs. not), injected heroin in the past month (yes vs. no), injected both heroin and cocaine in the past month (yes vs. no), injected cocaine in the past month (yes vs. no), and number of days of injecting drugs in the past month (≤5 days, 6–14 days, or 15–29 days vs. every day).

b Per 100 persons.

c For the outcome “any risk behavior,” on the ratio scale the model excluded the “number of days injected” variable because of model convergence issues. Models for the overall effect also excluded having injected cocaine. The stratified model for individual, disseminated, and composite effects also excluded having spent time in jail, heroin use, and having injected cocaine.