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. Author manuscript; available in PMC: 2019 Sep 12.
Published in final edited form as: J Am Chem Soc. 2018 Aug 29;140(36):11495–11501. doi: 10.1021/jacs.8b07461

Figure 1.

Figure 1.

Integration of Virion Display (VirD) with virion oscillators for studying membrane proteins. (a) Displaying human GPCRs on HSV-1 envelope with VirD. (b) Fabricating virion oscillators. Each virion oscillator consisting of a virion tethered to a gold surface with 63 nm long polyethylene glycol (PEG) linkers. The PEG linker contains a thiol and a N-hydroxysuccinimide (NHS) on its two ends, where the thiol group binds to the gold surface and the NHS group cross-links the virion via NHS-amine reaction.