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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Cancer Res. 2012 Sep 7;72(21):5529–5536. doi: 10.1158/0008-5472.CAN-12-1824

Table 2.

Cumulative dose and final organ depositions for beagle dogs exposed to 239Pu(NO3)4

Dog ID# 1 2 3 4 5 6 7 8 9 10 11 12 13
Gender F M F F F M M M F F M M F
Survival time postexposure (years) 14 11 11 12 9 13 12 12 10 10 9 4 3
Cause of death Bronchiolo-alveolar carcinoma Malignant mesothelioma Papillary adenocarcinoma of lung Interstitial pneumonitis Adenocarcinoma of lung Osteosarcoma Intrahepaticbile duct carcinoma Brcnchiolo-alveolar carcinoma Osteosarcoma of pelvis Pyometra Pulmonary papillary adenocarcinoma Metestic osteosarcoma Radiation pneumonitis
Initial lung
Burden (kBq) 3.7 7.1 8.6 9.2 9.5 9.9 10.3 10.9 12.8 13.1 17.0 89.2 92.8
Final lung
Burden (kBq) 0.01 0.05 0.06 0.03 0.03 0.03 0.04 0.05 0.03 0.02 0.16 3.40 4.70
Final LNTH
Burden (kBq) 0.02 0.03 0.19 0.02 0.02 0.03 0.05 0.03 0.04 0.03 0.04 0.47 0.37
Final
Skeleton 1.71 1.92 2.22 2.01 2.76 3.61 5.02 2.95 3.96 4.14 6.33 33.7 29.7
 Burden (kBq)
Final liver
Burden (kBq) 0.48 1.76 1.99 1.23 3.78 2.29 1.89 2.63 1.03 1.65 6.78 39.5 13.7
Final body
Burden (kBq) 2.22 3.75 4.46 3.29 6.58 5.96 7.01 5.65 5.06 5.85 13.31 77.07 48.47
Lung dose (mGy) 600 770 1240 1060 1040 860 840 1330 1570 1520 1830 6570 9550
LNTH Dose (mGy) 1730 1660 2560 2540 1750 2190 1980 3210 3110 3040 2990 4040 4660