Table 2.
HBsAg clearance and response at weeks 48 and 72
| Clinical information | Switch-to N (%) | Add-on N (%) | ETV N (%) | P-value |
|---|---|---|---|---|
| Week 48 | ||||
| N | 22 | 26 | 53 | |
| Clearance | 2 (9%) | 4 (15%) | 0 (0%) | <0.05 |
| Seroconversion | 2 (9%) | 4 (15%) | 0 (0%) | <0.05 |
| Response | 13 (60%) | 9 (38%) | 1 (2%) | <0.001 |
| Week 72 | ||||
| N | 22 | 26 | 53 | |
| Clearance | 2 (9%) | 4 (15%) | 0 (0%) | <0.05 |
| Seroconversion | 2 (9%) | 4 (15%) | 0 (0%) | <0.05 |
| Response | 13 (60%) | 10 (40%) | 1 (2%) | <0.001 |
Notes: Fisher’s exact test. The definition of response is HBsAg reduction >1 log IU/mL.
Abbreviations: ETV, entecavir; HBsAg, hepatitis B surface antigen.