Table 4.
HBsAg loss/reduction-associated factors
| Factors | Univariate
|
Multivariate
|
||
|---|---|---|---|---|
| Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
|
| ||||
| Age (years) | 0.883 (0.823–0.947) | 0.001 | ||
| BMI | 0.979 (0.860–1.107) | NS | ||
| ALT (IU/L) | 0.984 (0.947–1.024) | NS | ||
| AST (IU/L) | 1.002 (0.958–1.048) | NS | ||
| ALB (g/L) | 1.034 (0.963–1.110) | NS | ||
| PLT (/L) | 1.010 (0.999–1.022) | NS | ||
| Liver stiffness (kPa) | 0.949 (0.831–1.083) | NS | ||
| Treatment | 0.05 | |||
| HBsAg at baseline (log IU/mL) | 0.384 (0.219–0.676) | <0.001 | 0.434 (0.199–0.945) | 0.03 |
| HBsAg reduction at week 24 (log IU/mL) | 221.830 (22.121–2,224.565) | <0.001 | 83.864 (6.320–1,112.766) | <0.001 |
Note: Regression analyses presented as univariate and multivariate analyses.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; BMI, body mass index; HBsAg, hepatitis B surface antigen; PLT platelet.