Table 3.
Correlations Between Various Serologic Fibrosis Markers and Biochemical Parameters of Patients With NAA‐ALF at First Presentation
| Significance; P | HA* | 4COL7S† | WFA+‐M2BP‡ |
|---|---|---|---|
| Correlation Coefficient (R) | |||
| AST, IU/L | 0.0012 (0.40) | 0.31 | 0.15 |
| ALT, IU/L | 0.0078 (0.33) | 0.07 | 0.17 |
| Albumin, g/dL | 0.26 | 0.0006 (–0.42) | 0.15 |
| Ch‐E, IU/L | 0.51 | 0.13 | <0.0001 (–0.49) |
| T‐Bil, mg/dL | 0.66 | 0.24 | 0.11 |
| Creatinine, mg/dL | 0.57 | 0.46 | 0.94 |
| PT‐INR | <0.0001 (0.48) | 0.02 (0.28) | 0.03 (0.28) |
| Fibrinogen, mg/dL | 0.06 | 0.0005 (–0.42) | 0.0059 (–0.35) |
| FDP, mg/dL | 0.0001 (0.46) | 0.15 | 0.60 |
| AT‐III activity, % | 0.47 | 0.0025 (–0.38) | 0.0033 (–0.39) |
| NH3, mg/dL | 0.04 (0.24) | 0.009 (0.32) | 0.73 |
Spearman correlation analysis was used for each single analysis, and each result was collectively incorporated. Correlation coefficients (R) are shown in parentheses in cases with statistical significance. Number of study subjects included: *64 cases; †66 cases; ‡60 cases.
Abbreviations: AST, aspartate aminotransferase; Ch‐E, choline‐esterase; FDP, fibrin degradation products; T‐Bil, total bilirubin.