Table 5.
The SNPs in the bovine SIRT6 that alter or are adjacent to the cis-acting elements
| Locus | Genotype | Transcription factors | Cis-acting elements (Recognition sequencea) | Target strand |
|---|---|---|---|---|
| c.-84 C > T | C | Nuclear respiratory factor 1 | cacggCGCAtgcgcctt | (+) |
| C | C2H2 zinc finger transcription factors 15 | cacggcgcaTGCGcctt | (+) | |
| C | Mouse Krueppel like factor | cacggcgcatgcgCCTTgcga | (+) | |
| T | Nuclear respiratory factor 1 | cacggCGCAtgcgcctt | (+) | |
| T | C2H2 zinc finger transcription factors 15 | cacggcgcaTGCGcctt | (+) | |
| T | Mouse Krueppel like factor | cacggcgcatgcgCCTTgcga | (+) | |
| c.-1100 A > G | A | NKX homeodomain factors | agggtTGAGtgctgggagc | (−) |
| A | Brachyury gene, mesoderm developmental factor | gagctgatcaGGTGtcagggttgagtgct | (−) | |
| A | Calsenilin, presenilin binding protein, EF hand transcription factor | gtGTCAgggtt | (−) | |
| G | Selenocysteine tRNA activating factor | tgcacccgcagcTCCCagcactcaaccc | (+) | |
| G | NKX homeodomain factors | agggtTGAGtgctgggagc | (−) | |
| G | Brachyury gene, mesoderm developmental factor | gagctgatcaGGTGtcagggttgagtgct | (−) | |
| G | Calsenilin, presenilin binding protein, EF hand transcription factor | gtGTCAgggtt | (−) |
aSNP loci in tables, capital letters are core sequence of the transcription factors, and the letters with ci value > 85 are underlined