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. 2018 Nov 1;20:21. doi: 10.1186/s12575-018-0086-5

Table 2.

Enriched gene ontology terms in the CCAT1 wild-type versus CCAT1 knockout transcriptomes derived from differentially expressed genes (in the category of biological process)

ID Term Gene Count p Valuea
GO:0042493 response to drug 17 4.50E-05
GO:0055114 oxidation-reduction process 24 1.30E-04
GO:0031295 T cell costimulation 7 1.80E-03
GO:0008283 cell proliferation 15 3.00E-03
GO:0030522 intracellular receptor signaling pathway 5 3.40E-03
GO:0010951 negative regulation of endopeptidase activity 8 3.90E-03
GO:0090090 negative regulation of canonical Wnt signaling pathway 9 5.60E-03
GO:0008285 negative regulation of cell proliferation 15 6.00E-03
GO:0006805 xenobiotic metabolic process 6 9.20E-03
GO:0051897 positive regulation of protein kinase B signaling 6 1.20E-02
GO:0030449 regulation of complement activation 4 1.30E-02
GO:0006081 cellular aldehyde metabolic process 3 1.30E-02
GO:0048013 ephrin receptor signaling pathway 6 1.40E-02
GO:0001822 kidney development 6 1.40E-02
GO:0007612 learning 5 1.40E-02
GO:0032091 negative regulation of protein binding 5 1.40E-02
GO:0046685 response to arsenic-containing substance 3 1.90E-02
GO:0007568 aging 8 1.90E-02
GO:0060337 type I interferon signaling pathway 5 2.10E-02
GO:0042632 cholesterol homeostasis 5 2.10E-02
GO:0043524 negative regulation of neuron apoptotic process 7 2.20E-02
GO:0006954 inflammatory response 13 2.30E-02
GO:0016477 cell migration 8 2.40E-02
GO:0006636 unsaturated fatty acid biosynthetic process 3 2.50E-02
GO:0032570 response to progesterone 4 2.60E-02
GO:0038083 peptidyl-tyrosine autophosphorylation 4 2.80E-02
GO:0008360 regulation of cell shape 7 2.80E-02
GO:0032526 response to retinoic acid 4 3.00E-02
GO:0002223 stimulatory C-type lectin receptor signaling pathway 6 3.00E-02
GO:0003057 regulation of the force of heart contraction by chemical signal 2 3.30E-02
GO:0045785 positive regulation of cell adhesion 4 3.30E-02
GO:0042127 regulation of cell proliferation 8 3.40E-02
GO:0031668 cellular response to extracellular stimulus 3 3.50E-02
GO:0009615 response to virus 6 3.50E-02
GO:0030325 adrenal gland development 3 3.80E-02
GO:0071222 cellular response to lipopolysaccharide 6 3.90E-02
GO:0030154 cell differentiation 14 4.30E-02
GO:0014070 response to organic cyclic compound 4 4.70E-02
GO:0070668 positive regulation of mast cell proliferation 2 4.90E-02
GO:0060675 ureteric bud morphogenesis 2 4.90E-02
GO:0006991 response to sterol depletion 2 4.90E-02

aOnly GO terms with p value of less than 0.05 are shown