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. 2018 Oct 29;12:3625–3633. doi: 10.2147/DDDT.S176021

Table 1.

Characteristics of included studies

Study Country Study interval Study design LOEa Treatment regimen Number of patients, conbercept/ranibizumab

Cai and Peng,17 2016 People’s Republic of China 2013–2015 Retrospective 2b Monthly 30/30
Cui et al,18 2018 People’s Republic of China 2014–2015 Retrospective 2b As-needed 83/85
Huang et al,19 2018 People’s Republic of China 2013–2016 Retrospective 2b Monthly for 3 months then as-needed 35/44
Li et al,20 2018 People’s Republic of China 2016–2017 RCT 2b Monthly for 3 months then as-needed 20/20
Lv et al,21 2016 People’s Republic of China 2013–2015 RCT 2b Monthly for 3 months then as-needed 42/42
Niu et al,22 2016 People’s Republic of China 2014–2015 RCT 2b Monthly 20/20
Yang,23 2018 People’s Republic of China 2014–2016 RCT 2b As-needed 24/24
Zhang and Zhao,24 2016 People’s Republic of China 2014–2016 RCT 3b Monthly 25/25
Zhang,25 2017 People’s Republic of China 2015–2016 RCT 2b Monthly 20/20
Zhang and Bai,26 2017 People’s Republic of China 2014–2016 RCT 3b Monthly 49/49
Zhao and Bai,27 2015 People’s Republic of China 2013–2014 Retrospective 2b Monthly for 3 months then as-needed 30/31
Zheng,28 2017 People’s Republic of China 2013–2014 RCT 2b Monthly for 3 months then as-needed 42/43

Note:

a

Based on US Preventive Services Task Force grading system.

Abbreviations: LOE, level of evidence; RCT, randomized control trial.