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. 2018 Nov 1;12(11):e0006814. doi: 10.1371/journal.pntd.0006814

Table 1. Characteristics of the patients, by treatment and control group.

Characteristics Valid number Treatment
(n: 493)
Control
(n: 1320)
P-value
Age—mean (SD) 1813 54.1±11.5 59.4±12.5 <0.001
Female sex—n (%) 1813 337/493 (68.4) 893/1320 (67.7) 0.755
Illiterate—n (%) 1807 149/493 (30.2) 600/1314 (45.7) <0.001
Family monthly income—US$ 1306 370.87±203.04 417.39+209.56 <0.001
Duration of ChD > 10 yr—n (%) 1768 355/484 (73.3) 728/1284 (56.7) <0.001
Hypertension—n (%) 1813 280/493 (56.8) 852/1320 (64.5) <0.001
Diabetes mellitus—n (%) 1813 34/493 (6.9) 133/1320 (10.1) <0.001
Pacemaker—n (%) 1792 24/493 (5.0) 86/1299 (6.6) 0.291
Medication—n (%)
 Diuretic 1790 195/487 (40.0) 670/1303 (51.4) <0.001
 Digoxin 1795 22/487 (4.5) 104/1308 (8.0) <0.001
 Amiodarone 1749 87/464 (18.8) 324/1283 (25.3) <0.001
 Beta-blocker 1791 41/486 (8.4) 91/1305 (7.0) 0.210
 ACE inhibitor 1790 128/487 (26.3) 381/1303 (29.2) 0.150
 ARA 1791 125/487 (25.7) 373/1304 (28.6) 0.153
ECG typical ChD—n (%) 1779 233/491 (47.3) 773/1288 (60.0) <0.001
High age-adjusted NT-ProBNP n (%) 1810 30/492 (6.1) 175/1318 (13.3) <0.001
PCR positivity—n (%) 1813 82/493 (16.6) 481/1320 (36.4) <0.001
Mortality in 2-year follow-up 1813 14/493 (2.8) 100/1320 (7.6) <0.001

ACE = Angiotensin converting enzyme; ARA = angiotensin receptor antagonists; ECG = Electrocardiogram; NT-ProBNP = N-terminal of the prohormone brain natriuretic peptide; PCR = Polymerase-chain-reaction.