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. 2018 Nov 1;13(11):e0201682. doi: 10.1371/journal.pone.0201682

Fig 1. Three mutation subtypes of EGFR exon19.

Fig 1

The mutation pattern of group CD(codon deletion), with a deletion of one or more original codons(A); The mutation pattern of group CSS(codon substitution and skipping), with a deletion of one or two nucleotides but the residues could be translated into a new amino acid without changing following amino acid sequence(B); The mutation pattern of group CD/CSS+SNV(codon deletion or codon substitution and skipping plus SNV), exclude CD or CSS, there’s another SNV nearby the deletion region(C).