Table 2. Average hemodynamic evolution throughout pregnancy of total body water (TBW), extracellular water (ECW), intracellular water (ICW) and ECW/TBW (ECW%).

	Pregnancy outcome	First trimester	ΔT1-T2 (P-value)	Second trimester	ΔT2-T3 (P-value)	Third trimester
TBW (L)
	UP	33.2(32.8–33.6)	0.001	34.2(33.8–34.5)	0.001	35.3(34.8–35.9)
	EPE	35.0(33.0–36.9)	0.012	37.2(35.7–38.7)	0.010	40.9(39.3–42.6)
	LPE	33.0(31.8–34.1)	0.044	34.0(32.9–35.1)	0.001	40.1(39.2–40.9)
	GH	33.1(32.0–34.2)	0.020	34.1(33.1–35.2)	0.001	37.1(36.2–38.1)
	SGA	32.0(31.3–32.8)	0.001	33.0(32.3–33.7)	0.001	34.2(33.4–34.9)
	EH	33.1(32.8–33.5)	0.001	34.1(33.8–34.5)	0.001	35.4(34.8–35.9)
ECW (L)
	UP	14.2(14.0–14.4)	0.001	14.9(14.7–15.1)	0.001	15.9(15.6–16.2)
	EPE	15.5(14.6–16.5)	0.005	16.7(15.9–17.5)	0.001	20.1(19.2–20.9)
	LPE	14.2(13.6–14.8)	0.002	14.9(14.3–15.5)	0.001	19.1(18.6–19.5)
	GH	14.3(13.7–14.8)	0.001	14.9(14.4–15.5)	0.001	16.8(16.3–17.3)
	SGA	13.7(13.3–14.1)	0.001	14.4(13.9–14.7)	0.001	15.3(14.9–15.7)
	EH	14.2(14.0–14.4)	0.001	14.8(14.7–15.0)	0.001	15.9(15.6–16.1)
ICW (L)
	UP	18.9(18.8–19.1)	0.001	19.2(19.1–19.4)	0.001	19.7(19.5–19.9)
	EPE	19.6(18.9–20.4)	0.001	20.5(19.8–21.1)	0.023	21.1(20.4–21.8)
	LPE	18.6(18.2–19.1)	0.062	19.0(18.5–19.4)	0.001	21.1(20.8–21.5)
	GH	18.9(18.5–19.4)	0.005	19.3(18.8–19.7)	0.001	20.3(19.9–20.6)
	SGA	18.4(18.0–18.7)	0.001	18.7(18.3–19.0)	0.001	19.1(18.8–19.4)
	EH	18.9(18.8–19.1)	0.001	19.2(19.1–19.4)	0.001	19.7(19.5–19.9)
ECW%
	UP	43.0(42.8–43.1)	0.001	43.7(43.5–43.8)	0.001	44.6(44.3–44.9)
	EPE	44.4(43.5–45.4)	0.078	45.1(44.4–45.9)	0.001	48.6(47.9–49.4)
	LPE	43.3(42.8–43.8)	0.002	44.0(43.5–44.5)	0.001	47.2(46.8–47.6)
	GH	43.3(42.7–43.8)	0.002	43.8(43.4–44.4)	0.001	45.6(45.2–46.1)
	SGA	42.9(42.7–43.1)	0.001	43.6(43.4–43.8)	0.001	44.5(44.2–44.7)
	EH	42.9(42.8–43.1)	0.001	43.6(43.4–43.8)	0.001	44.5(44.3–44.8)

UP, uncomplicated pregnancy; EPE, early-onset preeclampsia; LPE, late-onset preeclampsia; GH, gestational hypertension; SGA, small for gestational age neonates; EH, essential hypertension; TBW, total body water; ECW, extracellular water; ICW, intracellular water; ECW%, fraction of extracellular water. Data are presented as corrected least-square means ± SD, representative for a nulliparous woman aged 30 years with BMI 23 kg/m². Numbers of assessments per group per trimester are presented in Fig 1.