Table 3. Average evolution throughout pregnancy of cardiac output (CO) and cardiac index (CI).

	Pregnancy outcome	First trimester	ΔT1-T2 (P-value)	Second trimester	ΔT2-T3 (P-value)	Third trimester
CO (L/min)
	UP	6.9(6.8–7.0)	0.001	7.7(7.6–7.8)	0.613	7.6(7.5–7.8)
	EPE	6.5(5.9–7.1)	0.764	6.4(6.0–6.8)	0.087	6.8(6.5–7.2)
	LPE	6.8(5.8–7.2)	0.139	7.1(6.8–7.5)	0.963	7.1(6.9–7.3)
	GH	6.6(6.3–6.8)	0.001	7.3(7.1–7.6)	0.313	7.3(7.0–7.5)
	SGA	6.5(6.3–6.8)	0.004	7.3(7.1–7.5)	0.600	7.2(7.0–7.5)
	EH	6.9(6.8–7.0)	0.001	7.7(7.6–7.8)	0.800	7.7(7.5–7.9)
CI (L/min/m2)
	UP	4.0(3.9–4.1)	0.001	4.4(4.3–4.4)	0.001	4.2(4.1–4.3)
	EPE	3.7(3.4–4.1)	0.705	3.7(3.5–3.9)	0.543	3.6(3.4–3.8)
	LPE	4.0(3.7–4.1)	0.383	4.0(3.9–4.2)	0.020	3.8(3.7–3.9)
	GH	3.9(3.7–4.1)	0.001	4.3(4.1–4.4)	0.001	3.9(3.7–4.0)
	SGA	3.9(3.8–4.0)	0.001	4.2(4.1–4.3)	0.001	4.1(4.0–4.2)
	EH	3.9(3.6–4.1)	0.001	4.3(4.0–4.5)	0.090	4.5(4.2–4.7)

UP, uncomplicated pregnancy; EPE, early-onset preeclampsia; LPE, late-onset preeclampsia; GH, gestational hypertension; SGA, small for gestational age neonates; EH, essential hypertension; CO, cardiac output; CI, cardiac index. CO is expressed as corrected least-square means ± SD, representative for a nulliparous woman aged 30 years with BMI 23 kg/m². CI is expressed as CO/body surface area, and corrected values representative for a nulliparous woman aged 30 years. Numbers of assessments per group per trimester are presented in Fig 1.