Table 4. Positive or negative differences for first trimester values of total body water (TBW), extracellular water (ECW), intracellular water (ICW), ECW/TBW (ECW%), cardiac output (CO) and cardiac index (CI) as well as their inter-trimestrial changes relative to uncomplicated pregnancies.

Pregnancy outcome	Parameter	First trimester values		Gestational evolution
		Difference compared to UP	P-value	P-value
EPE
	TBW	1,78	0,078	0,001
	ECW	1,3	0,01	<0,001
	ICW	0,66	0,086	0,039
	ECW%	1,48	0,002	<0,0001
	CO	-0,42	0,173	0,012
	CI	-0,27	0,0119	0,045
LPE
	TBW	0,006	0,991	<0,001
	ECW	0,099	0,746	<0,001
	ICW	-0,154	0,524	<0,001
	ECW%	0,385	0,179	<0,001
	CO	-0,079	0,647	0,015
	CI	-0,064	0,501	0,0021
GH
	TBW	-0,024	0,967	0,005
	ECW	0,107	0,707	0,009
	ICW	-0,0004	0,998	0,019
	ECW%	0,366	0,176	0,0359
	CO	-0,364	0,001	0,628
	CI	-0,147	0,122	0,0479
EH
	TBW	0,236	0,731	0,6781
	ECW	0,106	0,779	0,957
	ICW	0,158	0,6312	0,51
	ECW%	0,326	0,339	0,213
	CO	0,026	0,887	0,068
	CI	-0,169	0,161	0,0072
SGA
	TBW	-1,13	0,001	0,8987
	ECW	-0,51	0,007	0,212
	ICW	-0,59	<0,001	0,48
	ECW%	-0,15	0,397	0,1214
	CO	-0,38	<0,001	0,596
	CI	-0,13	0,012	0,789

UP, uncomplicated pregnancy; EPE, early-onset preeclampsia; LPE, late-onset preeclampsia; GH, gestational hypertension; EH, essential hypertension; SGA, small for gestational age neonates; TBW, total body water; ECW, extracellular water; ICW, intracellular water; ECW%, fraction of extracellular water; CO, cardiac output; CI, cardiac index. Numbers of assessments per group per trimester are presented in Fig 1.