Table 2. Incidence rates (per 1000 PYFU) of selected most common OIs stratified by current CD4 cell count in a cohort of patients on ART followed up for 10 years.
CD4 cell stratum (cells/μL) | ||||
---|---|---|---|---|
<100 | 100–199 | 200–349 | ≥350 | |
Number of events | 69 | 38 | 34 | 22 |
Incidence rate (95% CI) |
1507.5 (1190.7–1908.7) |
359.9 (261.9–494.6) |
95.0 (67.9.5–133.0) |
9.8 (6.4–14.9) |
Oral candidiasis | 964.2 (707.3–1314.5) |
199.3 (131.3–302.8) |
23.0 (11.9–44.1) |
3.7 (2.0–6.9) |
Tuberculosis | 386.3 (246.4–605.7) |
125.9 (78.2–202.5) |
22.2 (11.6–42.8) |
2.5 (1.2–5.2) |
Herpes zoster | 156.9 (74.8–329.1) |
58.1 (27.7–121.8) |
43.3 (27.6–67.9) |
3.2 (1.7–6.2) |
Cryptococcal meningitis | 227.6 (122.4–422.9) |
0 | 2.2 (0.3–16.0) |
0 |
ART: antiretroviral therapy; CI: confidence interval; OI: opportunistic infection; PYFU: person-years of follow-up