Table 1. M. xanthus ΔpilR suppressor mutations.
Strain | Mutation location& |
Locus | Gene Characteristic^ | Nucleotide change+ | Amino acid change$ |
---|---|---|---|---|---|
C1* | NA | ||||
C2 | 2377162 5207011 |
Intergenic mxan_4246 |
SK |
TT to CC C181T |
Q61Stop |
C3 | 5206543 | mxan_4246 | SK | C649T | Q217Stop |
C4 | 5206543 | mxan_4246 | SK | C649T | Q217Stop |
C5 | 5206345 | mxan_4246 | SK | C847T | Q283Stop |
C6 | 5206106 | mxan_4246 | SK | Δ-1(1085) | FS-361 |
C7 | 5206087 | mxan_4246 | SK | Δ-1(1104) | FS-368 |
C8 | 5206087 7443662 |
mxan_4246 mxan_6013 |
SK DnaJ/PilZ |
Δ-1(1104) C601T |
FS-368 P201S |
C9 | 5199422 | mxan_4240 | Nla/RR | T260A | V87E |
&, Mutation position based on M. xanthus DK1622 [27].
^, SK = sensor histidine kinase, Nla/RR (NtrC-like activator/Response regulator).
+, Nucleotide change listed as: consensus base/position in gene/suppressor mutation.
$, Amino acid change listed as: consensus amino acid/position in protein/amino acid change; Stop (stop codon), FS (frame shift).
*, NA = Not applicable, no mutation was identified.