Table 2:
Pearson correlation coefficients between puff count, puff duration, inter-puff interval, frequency of puff clusters, and measures of e-liquid consumption and nicotine intake and exposure.
| Amount of e-liquid consumed† | Amount of nicotine inhaled† | Cmax | AUC0→90 | |
|---|---|---|---|---|
| Strawberry e-liquid | ||||
| Puff count | 0.72** | 0.72** | 0.45 | 0.43 |
| Puff duration | 0.27 | 0.27 | 0.16 | 0.21 |
| Inter-puff interval | −0.50 | −0.50 | −0.32 | −0.30 |
| 1–5 puffs (n) | −0.28 | −0.28 | 0.11 | 0.06 |
| 6–10 puffs (n) | 0.20 | 0.20 | 0.27 | 0.22 |
| >10 puffs (n) | 0.69** | 0.69** | 0.27 | 0.30 |
| Tobacco e-liquid | ||||
| Puff count | 0.83*** | 0.83*** | 0.68** | 0.71* |
| Puff duration | 0.59* | 0.59* | 0.59* | 0.53* |
| Inter-puff interval | −0.53 | −0.53 | −0.41 | −0.45 |
| 1–5 puffs (n) | −0.21 | −0.21 | −0.05 | −0.11 |
| 6–10 puffs (n) | 0.31 | 0.31 | 0.26 | 0.30 |
| >10 puffs (n) | 0.74** | 0.74** | 0.57* | 0.62* |
| Usual brand e-liquids | ||||
| Puff count | 0.82*** | 0.08 | −0.10 | −0.10 |
| Puff duration | −0.11 | −0.09 | −0.05 | 0.07 |
| Inter-puff interval | −0.72** | −0.12 | 0.06 | 0.13 |
| E-liquid nicotine | −0.62* | 0.52 | 0.65* | 0.62* |
| 1–5 puffs (n) | −0.58* | −0.14 | −0.04 | −0.04 |
| 6–10 puffs (n) | 0.36 | 0.30 | 0.16 | 0.09 |
| >10 puffs (n) | 0.85*** | 0.10 | −0.06 | −0.05 |
Note: Data are for all 14 participants;
p < 0.05;
p < 0.01;
p < 0.001;
statistics are identical for amount of e-liquid consumed and amount of nicotine inhaled for the strawberry and tobacco e-liquids, respectively, because the nicotine concentration of each of these e-liquid was fixed during the study. Amount of nicotine inhaled is a function of amount of e-liquid consumed and e-liquid nicotine concentration.