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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Drug Alcohol Depend. 2018 May 31;189:42–48. doi: 10.1016/j.drugalcdep.2018.04.032

Table 2:

Pearson correlation coefficients between puff count, puff duration, inter-puff interval, frequency of puff clusters, and measures of e-liquid consumption and nicotine intake and exposure.

Amount of e-liquid consumed Amount of nicotine inhaled Cmax AUC0→90
Strawberry e-liquid
Puff count 0.72** 0.72** 0.45 0.43
Puff duration 0.27 0.27 0.16 0.21
Inter-puff interval −0.50 −0.50 −0.32 −0.30
1–5 puffs (n) −0.28 −0.28 0.11 0.06
6–10 puffs (n) 0.20 0.20 0.27 0.22
>10 puffs (n) 0.69** 0.69** 0.27 0.30
Tobacco e-liquid
Puff count 0.83*** 0.83*** 0.68** 0.71*
Puff duration 0.59* 0.59* 0.59* 0.53*
Inter-puff interval −0.53 −0.53 −0.41 −0.45
1–5 puffs (n) −0.21 −0.21 −0.05 −0.11
6–10 puffs (n) 0.31 0.31 0.26 0.30
>10 puffs (n) 0.74** 0.74** 0.57* 0.62*
Usual brand e-liquids
Puff count 0.82*** 0.08 −0.10 −0.10
Puff duration −0.11 −0.09 −0.05 0.07
Inter-puff interval −0.72** −0.12 0.06 0.13
E-liquid nicotine −0.62* 0.52 0.65* 0.62*
1–5 puffs (n) −0.58* −0.14 −0.04 −0.04
6–10 puffs (n) 0.36 0.30 0.16 0.09
>10 puffs (n) 0.85*** 0.10 −0.06 −0.05

Note: Data are for all 14 participants;

*

p < 0.05;

**

p < 0.01;

***

p < 0.001;

statistics are identical for amount of e-liquid consumed and amount of nicotine inhaled for the strawberry and tobacco e-liquids, respectively, because the nicotine concentration of each of these e-liquid was fixed during the study. Amount of nicotine inhaled is a function of amount of e-liquid consumed and e-liquid nicotine concentration.