Table 3.

Multivariable Analyses of Recovery after Oral Anticoagulation ICH

Variable	Functional Recovery^*
	RETRACE		MGH		ERICH		All Studies
	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
CHA₂DS₂-VASc Score (for 1 point increase)	0.85 (0.73 – 0.99)	0.036	0.78 (0.59 – 1.02)	0.075	0.84 (0.68 – 1.04)	0.11	0.83 (0.79 – 0.86)	<0.001
OAT Resumption	1.88 (1.05 – 3.37)	0.035	2.10 (1.04 – 4.25)	0.041	1.77 (0.98 – 3.19)	0.061	1.89 (1.32 – 2.70)	<0.001
Variable	mRS Score Change^**
	RETRACE		MGH		ERICH		All Studies
	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
CHA₂DS₂-VASc Score (for 1 point increase)	0.90 (0.83 – 0.98)	0.012	0.82 (0.70 – 0.96)	0.013	0.85 (0.74 – 0.98)	0.025	0.88 (0. 82 – 0.93)	<0.001
OAT Resumption	1.66 (1.10 – 2.51)	0.017	1.77 (1.13 – 2.77)	0.014	1.58 (1.06 – 2.36)	0.027	1.66 (1.30 – 2.12)	<0.001

All analyses adjusted for discharge modified Rankin scale, ICH location, and exposure to antiplatelet agents.

defined as achieving mRS ≤3 if mRS > 3 at discharge

^**

difference in mRS score between one-year follow-up and discharge, effect size calculated for one-point decrease in mRS

Abbreviations: 95% CI = 95% Confidence Interval, mRS = modified Rankin scale, OAT = Oral Anticoagulation Treatment, OR = Odds Ratio.