Table 2.
Differentially regulated miRNAs in the villus-crypt axis have genomic targets among the putative proteins in which the expression profile was affected by CD98 overexpression.
| Putative targets | miRNAs targeting the putative target gene | # of miRNAs | |
|---|---|---|---|
| Single Target | Multiple Targets | ||
| Prss1 | miR-17-3p | 1 | |
| Gpi1 | miR-425-5p, miR-150-5p | 2 | |
| Eef2 | miR-322-5p, miR-497-5p | miR-709, miR-326-3p, miR-484 | 5 |
| Actb | miR-132-3p, miR-1a-3p | miR-18a-5p, miR-802-5p | 4 |
| Mttp | miR-30a-5p, miR-30e-5p | 2 | |
| Cps1 | miR-151-5p | 1 | |
| Krt78 | miR-31-5p, miR-134-5p | miR-199a-5p | 3 |
| Tfrc | miR-7a-5p, miR-221-3p, miR-365-3p, miR-7b-5p | miR-30a-5p, miR-30e-5p, miR-130b-5p | 7 |
| Ezr | miR-17-3p | 1 | |
| Hspa5 | miR-374b-5p, miR-350-3p | miR-130b-3p, miR-301a-3p, miR-351-5p, miR-130a-3p, miR-148a-3p, miR-152-3p, miR-125a-5p, miR-125b-5p, miR-150-5p, miR-351-5p | 12 |
| Immt | miR-191-3p | miR-342-3p, miR-802-5p, miR-203-5p | 4 |
| Dlat | miR-191-5p, miR-194-5p, miR-872-3p | miR-421-3p | 4 |
| Atic | miR-30e-3p, miR-455-3p | miR-18a-5p, miR-342-3p, miR-709, miR-326-3p | 6 |
| Me2 | miR-106a-5p, miR-17-5p, miR-93-5p | miR-351-5p, miR-101a-3p, miR-144-3p, miR-125a-5p, miR-125b-5p, miR-203-5p | 9 |
| Cct6a | miR-26a-5p, miR-26b-5p | miR-101a-3p, miR-144-3p, miR-7a-1-3p, miR-130b-5p | 6 |
| Canx | miR-130b-3p, miR-301a-3p, miR-130a-3p, miR-144-3p, miR-148a-3p | 5 | |
| P4hb | miR-199a-5p, miR-484 | 2 | |
| Pkm | miR-378a-5p | miR-130b-5p | 2 |
| Atp5b | miR-23a-3p | 1 | |
| Fkbp4 | miR-21a-3p, miR-137-3p | miR-181a-5p, miR-181d-5p | 4 |
| Pm20d1 | miR-143-3p, miR-674-3p | 2 | |
| Cndp2 | miR-351-5p, miR-709, miR-125a-5p, miR-125b-5p, miR-351-5p, miR-674-3p | 6 | |
| Krt2 | miR-23a-3p | 1 | |
| Calr | miR-22-5p | miR-709, miR-148a-3p, miR-152-3p, miR-143-3p | 5 |
| Pdia6 | miR-106b-5p, miR-20a-5p | miR-181a-5p, miR-181d-5p, miR-23a-3p | 5 |
| Capza1 | miR-181a-5p, miR-181d-5p, miR-23a-3p, miR-30a-5p, miR-30e-5p, miR-7a-1-3p | 6 | |
| Taldo1 | miR-19b-3p | miR-130b-3p, miR-301a-3p, miR-130a-3p | 4 |
| Rpsa | miR-425-5p | 1 | |
| Mlec | miR-399-5p | miR-421-3p, miR-674-3p | 3 |
| Total | 29 | 32 | 31 |
miRNAs listed in each row represents miRNAs targeting the putative target gene listed in the corresponding row. miRNAs listed under “Single Target” refer to miRNAs that solely target the gene in the same row, whereas the miRNAs listed under “Multiple Targets” refer to miRNAs targeting genes listed elsewhere in the table, including the one it is listed under. Values in very far right panel refer to the number of miRNAs targeting the putative gene in the corresponding row.