Table 2.
Receiver operator characteristic (ROC) curve of C-ACT score performance in classifying GINA categories (well controlled v/s all other categories) in 105 children with asthma
| Cut-point value of C-ACT score | Sensitivity % | Specificity % | Youden Index | Correctly classified % | Positive likelihood ratio | Negative likelihood ratio |
|---|---|---|---|---|---|---|
| 9 | 100.00 | 6.25 | 0.0625 | 57.14 | 1.0667 | 0 |
| 11 | 100.00 | 8.33 | 0.0833 | 58.10 | 1.0909 | 0 |
| 12 | 98.25 | 8.33 | 0.0658 | 57.14 | 1.0718 | 0.2105 |
| 13 | 98.25 | 16.67 | 0.1492 | 60.95 | 1.1789 | 0.1053 |
| 14 | 94.74 | 18.75 | 0.1349 | 60.00 | 1.166 | 0.2807 |
| 15 | 94.74 | 22.92 | 0.1766 | 61.90 | 1.229 | 0.2297 |
| 16 | 94.74 | 27.08 | 0.2182 | 63.81 | 1.2992 | 0.1943 |
| 17 | 94.74 | 35.42 | 0.3016 | 67.62 | 1.4669 | 0.1486 |
| 18 | 94.74 | 54.17 | 0.4891 | 76.19 | 2.067 | 0.0972 |
| 19 | 94.74 | 70.83 | 0.6557 | 83.81 | 3.2481 | 0.0743 |
| 20 | 85.96 | 81.25 | 0.6721 | 83.81 | 4.5848 | 0.1727 |
| 21 | 80.70 | 87.50 | 0.682 | 83.81 | 6.4561 | 0.2206 |
| 22 | 64.91 | 91.67 | 0.5658 | 77.14 | 7.7895 | 0.3828 |
| 23 | 49.12 | 97.92 | 0.4704 | 71.43 | 23.579 | 0.5196 |
| 24 | 38.60 | 97.92 | 0.3652 | 65.71 | 18.5264 | 0.6271 |
| 25 | 26.32 | 100.00 | 0.2632 | 60.00 | 0.7368 | |
| 26 | 14.04 | 100.00 | 0.1404 | 53.33 | 0.8596 | |
| 27 | 10.53 | 100.00 | 0.1053 | 51.43 | 0.8947 |
Area under ROC curve = 0.89, SE = 0.03, 95 confidence intervals 0.83–0.96
C-ACT Childhood Asthma Control Test, GINA Global Initiative for Asthma