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. 2018 Oct 26;5:101. doi: 10.3389/fnut.2018.00101

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Copyright © 2018 Moran, Al-Rammahi, Batchelor, Bravo and Shirazi-Beechey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Villus height and crypt depth measurements in wild type and Glp2r^−/− mice maintained on low- or high-CHO diets. (A) Representative light micrograms of small intestine of wild type and Glp2r^−/− mice fed either a low carbohydrate (LCHO) or high-carbohydrate (HCHO) diet as described in the method section. Images represent 10X magnification. (B) Morphometric analyses of villus height and crypt depths are shown as histograms, in μm ± SD. Low-CHO-fed wild type (□), High-CHO-fed wild type (), Low-CHO-fed Glp2r^−/− (), High-CHO-fed Glp2r^−/− (); n = 4 per group. Statistically significant results were determined using One-way ANOVA with Dunnett's multiple comparison post-test.

Inline graphic — Villus height and crypt depth measurements in wild type and Glp2r^−/− mice maintained on low- or high-CHO diets. (A) Representative light micrograms of small intestine of wild type and Glp2r^−/− mice fed either a low carbohydrate (LCHO) or high-carbohydrate (HCHO) diet as described in the method section. Images represent 10X magnification. (B) Morphometric analyses of villus height and crypt depths are shown as histograms, in μm ± SD. Low-CHO-fed wild type (□), High-CHO-fed wild type (), Low-CHO-fed Glp2r^−/− (), High-CHO-fed Glp2r^−/− (); n = 4 per group. Statistically significant results were determined using One-way ANOVA with Dunnett's multiple comparison post-test.