Table 1.
Studies that specifically focused on the initial dip in the ISOI and some other modalities (years: 2003–2018, source: Web of Science).
| Reference | Modality | Species | Alert/anesthetic | Stimulation | Area |
|---|---|---|---|---|---|
| Thompson et al., 2003 | O2 microelectrode | Cat | Anesthetic (thiopental) | Visual stimulus | Visual cortex (area 17) |
| Sheth et al., 2004 | ISOI | Rat | Anesthetic (halothane) | Whisker deflection and hindpaw stimulation | Barrel cortex |
| Thompson et al., 2004 | O2 microelectrode | Cat | Anesthetic (thiopental) | Visual stimulus | Visual cortex (area 17) |
| Suh et al., 2005 | ISOI | Rat | Anesthetic (urethane) | Hindlimb stimulation | Neocortex |
| Sheth et al., 2005 | ISOI | Rat | Anesthetic (halothane) | Hindpaw stimulation | Somatosensory cortex |
| Thompson et al., 2005 | O2 microelectrode | Cat | Anesthetic (thiopental) | Visual stimulus | Visual cortex (area 17) |
| Foster et al., 2005 | O2 microelectrode and NADH imaging | Rat | Anesthetic (halothane) | Hypoxia and synaptic activation | Hippocampal slices |
| Bahar et al., 2006 | ISOI | Rat | Anesthetic (urethane) | 4-amino-pyridine | Neocortex |
| Fukuda et al., 2006 | ISOI | Cat | Anesthetic (isoflurane) | Visual stimulus | Visual cortex |
| Suh et al., 2006a | ISOI | Human | Anesthetic (isoflurane and remyfentanyl) | Electrical stimulation | Motor, sensory and language cortex |
| Chen-Bee et al., 2007 | ISOI | Rat | Sodium pentobarbital | Whisker deflection | Somatosensory cortex |
| Prakash et al., 2007 | Optical spectroscopy | Rat and mice | Anesthetic (halothane) | Forepaw stimulation | Somatosensory cortex |
| Schiessl et al., 2008 | ISOI | Monkey | Anesthetic (isoflurane) | Visual stimulus | Visual cortex |
| Lesage et al., 2009 | ISOI | Rat | Anesthetic (isoflurane) | Spinal cord injury | Spinal cord |
| Ma et al., 2009 | ISOI | Human | Anesthetic (isoflurane and remyfentanyl) | Electrical stimulation | Motor, sensory and language cortex |
| Sirotin et al., 2009 | ISOI | Monkey | Alert | Visual stimulus | Visual cortex |
| Chen-Bee et al., 2010 | ISOI | Rat | Sodium pentobarbital | Whisker deflection | Somatosensory cortex |
| Lee et al., 2012 | ISOI and NIRS | Rat | Anesthetic (isoflurane) | Electrical stimulation | Somatosensory cortex |
| Ma et al., 2016 | ISOI | Cat | Anesthetic (isoflurane) | Transcorneal electrical stimulation | Visual cortex |
| Lu et al., 2017 | ISOI | Monkey | Anesthetic (isoflurane) | Moving light spot stimulus | Visual cortex |
| Sintsov et al., 2017 | ISOI | Rat | Anesthetic (isoflurane) | Whisker stimulation | Somatosensory cortex |