Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 2;7(11):83. doi: 10.1038/s41389-018-0093-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Quantitative real-time PCR results of relative expression levels of BRD2, BRD3, BRD4 in 39 pairs of RCC tissues and adjacent normal tissues. b Immunoblot analysis of BRD2 and BRD4 expression in 6 pairs of RCC tissues and adjacent normal tissues. Quantifications are shown in the panels below. c Knockdown efficiency of siBRD2 and BRD4 by immunoblot analysis. d Knockdown of BRD2 or BRD4 moderately inhibited the proliferation of RCC 786-O and A498 cells, while knocking down both of their expressions resulted in more significant anti-proliferative effects. Two-way ANOVA with multiple comparisons was used to compare each knocking down group to siControl group. Representative results were shown, error bars indicated standard deviation among technical replicates (n = 5 technical replicates per experiment). *p < 0.05; **p < 0.01; ***p < 0.001. The experiments were replicated 3 times to confirm the conclusion