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. 2018 Oct 26;9:1176. doi: 10.3389/fphar.2018.01176

Table 4.

Antibiotic and antifungal dose concentrations suggested for CF cell culture treatment.

Antibiotic Dose 10x Antibiotics type Indications
Tobramycin 8 μg/mL Aminoglycoside Gram-negative Bacteria
Amikacin 25 μg/mL Aminoglycoside Gram-negative Bacteria
Gentamicin 40 μg/mL Aminoglycoside Gram-negative Bacteria
Piperacillin-Tazobactam 50 μg/mL Beta-lactamase inhibitors Gram-positive Bacteria
Ticarcillin 250 μg/mL Beta-lactamase inhibitors Gram-positive Bacteria
Imipenem 2000 μg/mL Beta-lactamase inhibitors Gram-positive Bacteria
Meropenem 250 μg/mL Beta-lactamase inhibitors Gram-positive Bacteria
Ceftazidime 250 μg/mL Beta-lactamase inhibitors Gram-positive Bacteria
Oxazolidinone (Linezolid) 2 mg/mL Inhibitor on the ribosomal 50S Gram-positive Bacteria
Teicoplanin 60 μg/mL Semisynthetic glycopeptide Gram-positive Bacteria
Vancomycin 50 μg/mL Glycopeptide Gram-positive Bacteria
Ciprofloxacin 25 μg/mL Fluoroquinolone Gram-positive and negative Bacteria
Levofloxacin 100 μg/mL Fluoroquinolone Gram-positive and negative Bacteria
Trimethoprim + Sulfamethoxazole 25 μg/mL Sulfonamides Gram-positive and negative Bacteria
Colistimethate sodium 50 U/mL Polymyxin Multi-drug resistant Bacteria
Amphotericin B 25 μg/mL Macrocyclic polyene Antifungal