Table 5.

Postmortem concentration ratios in different biological samples for synthetic opioids (median, range, number of cases).

Analyte	Cardiac-to-femoral	Liver-to-femoral	Vitreous humor-to-femoral	References
Acetylfentanyl	1.2 (0.8–1.6) n = 4	3.8–5.7 n = 2	0.6–0.9 n = 2	Cunningham et al., 2016; Fort et al., 2016; McIntyre et al., 2016a; Yonemitsu et al., 2016
Butyryl fentanyl	0.6 (0.4–2.2) n = 3	0.4–0.9 n = 2	0.3 n = 1	Poklis et al., 2016; Staeheli et al., 2016
Fentanyl	(0.7–4.6) n = 54	6.6 (1.4–539.4) n = 75	1.5 (1.1–1.8) n = 3	Anderson and Muto, 2000; Krinsky et al., 2011, 2014; Palamalai et al., 2013; McIntyre et al., 2014; Bakovic et al., 2015
Furanyl fentanyl	1.5 n = 1	–	–	Martucci et al., 2017
Ocfentanyl	1.5 (1.1–3.1) n = 3	2 n = 1	0.8 n = 1	Coopman et al., 2016; Dussy et al., 2016; Allibe et al., 2018
AH–7921	0.4–1.1 n = 2	1.2–2.9 n = 2	0.4 n = 1	Vorce et al., 2014; Fels et al., 2017
MT-45	2 n = 1	36.4 n = 1	0.4 n = 1	Fels et al., 2017
U-47700	1.5 (0.7–2.6) n = 4	0.4 (0.003–8.9) n = 4	0.2–0.9 n = 2	Dziadosz et al., 2017; Rohrig et al., 2017