Table 1.
Characteristics of included studies.
| Studies | Total (N) | Entry-EF cut-off | Intervention group | Control group | Treatment duration | Outcomes | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sample size | Age | Intervention | Sample size | Age | Control | |||||
| Tian, 2011 | 120 | 50% | 60 | 60.30 ± 7.36 | Qili Qiangxin capsules, Benazepril hydrochloride tablets, Metoprolol tartrate tablets | 60 | 61.02 ± 7.89 | Benazepril hydrochloride tablets, Metoprolol tartrate tablets | 1 month | BNP, clinical efficacy rate, MLHFQ, clinical efficacy rate |
| Chang and Gong, 2014 | 160 | 45% | 80 | 62.41 | Conventional western medicine, decoction of CHM (radix pseudostellariae, ligusticum wallichii, lilium brownii, dried rehmannia root, astragalus, root of common peony, angelica sinensis, radix ophiopogonis, the root of red-rooted salvia, herba leonuri) | 80 | 61.32 | Conventional western medicine | 1 month | All-cause mortality, heart failure hospitalization |
| Zhou et al., 2014 | 160 | 45% | 80 | 60.54 | Conventional western medicine, decoction of CHM (radix pseudostellariae, dried rehmannia root, radix ophiopogonis, the root of red-rooted salvia, lilium brownii, astragalus, angelica sinensis, herba leonuri, ligusticum wallichii, root of common peony) | 80 | 61.32 | Conventional western medicine | 1 month | BNP |
| Sun and Gong, 2013 | 160 | 45% | 82 | 61.32 ± 5.4 | Imidapril, Bisoprolol, Aldactone, Isosorbide dinitrate, Yi Qi Yang Yin Huo Xue decoction (scrophularia ningpoensis, radix ophiopogonis, dried rehmannia root, astragalus, angelica sinensis, ligusticum wallichii, root of common peony, the root of red-rooted salvia, radix codonopsis) | 78 | 60.54 ± 5.08 | Imidapril, Bisoprolol, Aldactone, Isosorbide dinitrate | 30 days | Clinical efficacy rate |
| Liu et al., 2011a | 120 | 50% | 60 | 52.88 ± 0.34 | Conventional western medicine, Bawei Tongluo granules (leech, lumbricus, ligusticum wallichii, the root of red-rooted salvia, the root of kudzu vine, peach seed, safflower, honey-fried licorice root) | 60 | 54.32 ± 9.76 | Conventional western medicine, Bawei Tongluo granulation simulator | 8 week | Clinical efficacy rate, 6MWD, MLHFQ |
| Wang and Ouyang, 2016 | 210 | 50% | 105 | 65.6 ± 7.9 | Enalapril, Tongmai Baoxin Decoction (astragalus, the root of red-rooted salvia, herba leonuri, poria cocos, radix ginseng rubra, safflower, semen lepidii, sappanwood, cassia twig, atractylodes macrocephala koidz, radix ophiopogonis) | 105 | 64.4 ± 8.1 | Enalapril | 3 month | 6MWD, BNP, MLHFQ |
| Zhou and Hong, 2016 | 184 | 50% | 94 | 64.34 ± 3.32 | Conventional western medicine, Huoxue Lishui Decoction (astragalus, rhodiola rosea, root of common peony, ligusticum wallichii, the root of red-rooted salvia, semen lepidii, rhizoma alismatis, grifola) | 90 | 63.15 ± 12.37 | Conventional western medicine | 1 month | 6MWD, NT-pro BNP, clinical efficacy rate |
| Wei, 2016 | 120 | 45% | 60 | 61.2 ± 8.1 | Conventional western medicine, Qili Qiangxin Capsules, Trimetazidine Dihydrochloride Tablets | 60 | 61.9 ± 7.5 | Conventional western medicine | 4 week | Clinical efficacy rate |
| Yang and Suo, 2015 | 120 | 45% | 60 | 59.21 ± 4.75 | Enalapril, Metoprolol, Qili Qiangxin Capsules | 60 | 59.49 ± 4.82 | Enalapril, Metoprolol | 1 month | BNP |
| Wen, 2013; Yu, 2013 | 120 | 50% | 60 | 61.37 ± 6.32 | Conventional western medicine, decoction of CHM (astragalus, the root of red-rooted salvia, angelica sinensis, herba leonuri, ligusticum wallichii, root of common peony) | 60 | 62.02 ± 6.35 | Conventional western medicine | 4 week | 6MWD, BNP, all-cause mortality, heart failure hospitalization, clinical efficacy rate |
| Liu et al., 2016, 2017; Xie et al., 2016 | 120 | 45% | 60 | 76.7 ± 7.7 | Conventional western medicine, Jiawei Zhenwu decoction (radix aconiti carmichaeli, ginger, poria cocos, atractylodes macrocephala koidz, radix paeoniae alba, cassia twig, semen lepidii, rhodiola rosea, radix pseudostellariae, astragalus) | 60 | 76.3 ± 7.0 | Conventional western medicine | 4 week | 6MWD ‵ BNP ‵ SF-36 ‵ MLHFQ |
| Zhang, 2015a | 180 | 50% | 90 | 60–85 | Conventional western medicine, Wenxin Keli | 90 | 60-87 | Conventional western medicine | 12 week | Clinical efficacy rate |
| Ji, 2017 | 130 | 45% | 65 | 72.98 ± 2.69 | Conventional western medicine, Jiawei Zhenwu decoction (radix paeoniae alba, radix rehmanniae preparata, poria cocos, herba aristolochiae, ginger, atractylodes macrocephala koidz, angelica sinensis, radix codonopsis) | 65 | 73.34 ± 2.78 | Conventional western medicine | 21 days | SF-36, 6MWD |
| Shang, 2016 | 188 | 50% | 94 | 72.2 | Conventional western medicine, salvianolate, Shenmai injection | 94 | 72.2 | Conventional western medicine | 2 month | Clinical efficacy rate |
| Han et al., 2016 | 150 | 45% | 75 | 66.0 ± 4 | Conventional western medicine, benazepril, Danshen Chuanxiongqin injection | 75 | 68.0 ± 5 | Conventional western medicine | 14 days | NT-proBNP, clinical efficacy rate |
| Zhang, 2015b | 300 | 45% | 150 | 71.8 ± 4 | Conventional western medicine, Shuxuetong injection | 150 | 72.2 ± 3 | Conventional western medicine | 10 days | BNP, clinical efficacy rate |
| Liu et al., 2011b | 182 | 50% | 101 | 70.64 ± 9.29 | Conventional western medicine, Yixinshu capsules | 100 | 69.29 ± 7.01 | Conventional western medicine | 8 week | BNP |