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. 2018 Oct 26;9:1420. doi: 10.3389/fphys.2018.01420

Table 3.

Significant metabolic pathways that are related to these 10 herbs.

No. Pathway or process Count % Log10(P) Log10(q)
1 organic hydroxy compound metabolic process 80 15.24 −43.27 −39.27
2 response to inorganic substance 77 14.67 −39.17 −35.35
3 drug metabolic process 92 17.52 −38.76 −35.06
4 cellular response to organic cyclic compound 78 14.86 −36.75 −33.15
5 regulation of hormone levels 73 13.90 −35.79 −32.33
6 cellular response to nitrogen compound 78 14.86 −33.64 −30.30
7 regulation of ion transport 75 14.29 −32.02 −28.76
8 response to oxidative stress 63 12.00 −30.96 −27.74
9 regulation of homeostatic process 65 12.38 −30.25 −27.09
10 regulation of lipid metabolic process 51 9.71 −24.36 −21.61

“Count” is the number of target genes of the 10 CHMs with membership in the given ontology term. “%” is the percentage of total target genes of the 10 CHMs that are found in the given ontology term. “Log10(P)” is the p-value in log base 10. “Log10(q)” is the multi-test adjusted p-value in log base 10. The metabolic pathways are arranged in ascending order of their respective q-value.