Figure 3.

Histological images of metastatic prostate adenocarcinoma obtained from transanal full-thickness excisional biopsy. A: Hematoxylin and eosin (HE) staining showed a moderate to poorly differentiated adenocarcinoma characterized by tumor cells diffusely infiltrated into submucosa and muscularis propria, sparing the mucosal layer (original magnification ×100); B: Immunohistochemical stains were performed and the tumor cells were positive for prostate specific antigen (PSA, original magnification ×100).