Table 2.
Body and tissue weights of mice treated with or without teneligliptin for 10 weeks
| Diet | ND | HFD | |
|---|---|---|---|
| Treatment | Vehicle | Vehicle | Teneligliptin |
| Food intake (g·day−1) | 3.20 ± 0.04 | 2.83 ± 0.10 | 2.92 ± 0.15 |
| Body weight (g) | 29.5 ± 0.74 | 38.7 ± 1.91* | 25.9 ± 0.69# |
| Tissue weight (g/100 g body weight) | |||
| Inguinal WAT | 1.045 ± 0.074 | 2.418 ± 0.242* | 1.320 ± 0.189# |
| Epididymal WAT | 1.692 ± 0.192 | 4.285 ± 0.363* | 1.882 ± 0.504# |
| Mesenteric WAT | 0.904 ± 0.072 | 2.146 ± 0.289* | 0.674 ± 0.137# |
| Perirenal WAT | 0.799 ± 0.094 | 2.408 ± 0.203* | 0.998 ± 0.231# |
| Interscapular BAT | 0.311 ± 0.015 | 0.375 ± 0.037 | 0.261 ± 0.015# |
| Gastrocnemius | 1.020 ± 0.016 | 0.844 ± 0.042* | 1.057 ± 0.033# |
| Liver | 4.749 ± 0.072 | 4.099 ± 0.319 | 3.751 ± 0.262 |
| Kidney | 1.164 ± 0.014 | 1.018 ± 0.047* | 1.278 ± 0.055# |
The values are shown as means ± SE (n = 6–10).
*P < 0.05 compared with ND vehicle.
# P < 0.05 compared with HFD vehicle.