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. 2018 Sep 22;46(19):10246–10261. doi: 10.1093/nar/gky854

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Interaction of UP1+RGG and UP1 with the single stranded and G-quadruplex DNA monitored through ITC. Raw and fitted isotherms are shown and the equilibrium K_ds obtained upon fitting of the raw data is mentioned in each panel. (A, B) Interaction of UP1 with the single stranded Tel22ss DNA in the presence of 100 mM NaCl and 100 mM KCl respectively. (C, D) Interaction of UP1+RGG with the single stranded Tel22ss DNA in the presence of 100 mM NaCl and 100 mM KCl respectively. (E, F) Interaction of UP1 with the Na⁺ and K⁺ forms of Tel22 G-quadruplex DNA respectively. (G, H) Interaction of UP1+RGG with the Na⁺ and K⁺ forms of Tel22 G-quadruplex DNA respectively.