Table 2.

Thermodynamic parameters derived from ITC experiments for the titration of UP1 and UP1+RGG into telomere single-stranded and G-quadruplex DNA

S.No	Experiment	Salt (100 mM)	K d (μM)	ΔG (kcal/mol)	ΔH (kcal/mol)	TΔS (kcal/mol)	n
1	UP1–Tel22ss	NaCl	1.20 ± 0.31	-8.07 ± 2.05	−30.48 ± 1.428	−22.41 ± 3.478	1.73 ± 0.06
2	UP1–Tel22ss	KCl	1.23 ± 0.14	−8.05 ± 0.9	−25.32 ± 0.52	−17.27 ± 1.42	2.04 ± 0.03
3	UP1+RGG–Tel22ss	NaCl	1.04 ± 0.15	−8.15 ± 1.14	−24.65 ± 0.84	−16.50 ± 1.98	1.98 ± 0.05
4	UP1+RGG – Tel22ss	KCl	1.11 ± 0.15	−8.11 ± 1.08	−30.54 ± 0.7	−22.43 ± 1.79	1.70 ± 0.03
5	UP1–Tel22	NaCl	0.71 ± 0.14	−8.38 ± 1.68	−14.26 ± 0.37	−5.88 ± 2.05	2.08 ± 0.04
6	UP1–Tel22	KCl	5.62 ± 1.09	−7.15 ± 1.39	−17.84 ± 2.012	−10.69 ± 3.402	2.21 ± 0.20
7	UP1+RGG–Tel22	NaCl	0.60 ± 0.13	−8.48 ± 1.81	−24.84 ± 0.907	−16.36 ± 2.717	2.05 ± 0.06
8	UP1+RGG–Tel22	KCl	4.85 ± 0.60	−7.42 ± 0.88	−44.89 ± 4.84	−37.65 ± 5.72	1.72 ± 0.15