LECs |
Lens epithelial cells |
UV |
Ultraviolet |
TGF |
Transforming growth factor |
MLECs |
Mouse LECs |
RLECs |
Rat LECs |
HLECs |
Human LECs |
ECM |
Extra cellular matrix protein |
ROS |
Reactive oxygen species |
αSMA |
α-Smooth muscle actin |
βig-h3 |
TGF-β-induced protein |
PCO |
Posterior capsule opacification |
EMT |
Epithelial-mesenchymal transition |
ASF |
Anterior subcapsular fibrosis |
Tpms |
Tropomyosins |
FGF |
Fibroblast growth factor |
Prdx |
Peroxiredoxin |
LEDGF |
Lens epithelium-cell derived growth factor |
Hsp |
Heat shock protein |
TIE |
TGF β inhibitory elements |
Prdx6-/-
|
Prdx6-deficient |
DIGE |
Difference gel electrophoresis |
MALDI-TOF |
Matrix-assisted laser desorption/ionization time-of-flight |
MS |
Mass spectrometry |
ECLE |
Extracapsular lens extraction |
IOL |
Intra ocular lens |
EMyoT |
Epithelial-to-myofibroblastic transition |
MAPK/ERK |
Mitogen-activated protein kinase/extracellular signal–regulated kinase |
MEK |
Mitogen-activated protein kinase kinase |
CRISPR/Cas9 |
Clustered regularly interspaced short palindromic repeat/Cas9 |
Tpm2+/-
|
Tpm2 heterozygous knockout |