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. 2018 Sep 23;10(10):1366. doi: 10.3390/nu10101366

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effects of CGA on AKT phosphorylation and its downstream factors. (A) The time-dependent effect of CGA on the phosphorylation of AKT (T308 and S473). (B) The time-dependent effect of CGA on the phosphorylation of forkhead box O1 (FOXO1) and glycogen synthase kinase 3β (GSK3β). The histograms present the relative intensities of the detected protein bands. (C) The effect of CGA on the enzymatic activity of GSK3β. SC79 was used as the positive control. The histogram presents the activity of GSK3β at 600 s after the respective treatments. Each bar represents the mean ± SEM. * p < 0.05 vs. control; ** p < 0.01 vs. control; *** p < 0.001 vs. control (n = 3).