Table 2.

Classification statistics for unigenes (UG) and differentially expressed genes (up-regulated (UR) and down-regulated genes (DR)) in CBCVd-infected hop plant according to Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.

KEGG Categories	Number of			KEGG Categories	Number of
	UG	UR	DR		UG	UR	DR
Metabolism				Organismal System
Carbohydrate Metabolism	1457	168	54	Immune system	650	24	23
Energy metabolism	608	58	47	Endocrine system	692	66	29
Lipid metabolism	768	149	41	Circulatory system	93	8	3
Nucleotide metabolism	320	19	29	Digestive system	167	18	6
Amino acid metabolism	841	126	50	Excretory system	111	12	2
Metabolism of other amino acids	307	44	24	Nervous system	495	44	13
Glycan biosynthesis and metabolism	299	43	10	Sensory system	49	11	3
Metabolism of cofactors and vitamins	412	41	13	Development	74	5	6
Metabolism of terpenoids and polyketides	222	31	26	Aging	219	10	17
Biosynthesis of other secondary metabolites	453	110	10	Environmental adaptation	506	55	26
Xenobiotics biodegradation and metabolism	239	61	34
Enzyme families	921	106	41
Genetic information processing
Transcription	316	71	60
Translation	846	111	235
Folding, sorting and degradation	730	201	65
Replication and repair	271	63	60
RNA family	0	0	0
Cellular Process
Transport and catabolism	916	174	52	Unclassified
Cell growth and death	684	49	22	Metabolism	2007	44	11
Cellular community—eukaryotes	178	7	3	Genetic information processing	5896	6	5
Cellular community—prokaryotes	113	20	3	Cellular processes and signaling	1833	8	3
Cell motility	55	14	14	Viral protein family	0	0	0
Environmental information processing				Poorly characterized	585	8	6
Membrane transport	64	96	33
Signal transduction	2134	165	63
Signaling molecules and interaction	187	26	7
				Total	26,718	2272	1149