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. 2018 Sep 5;46(19):10157–10172. doi: 10.1093/nar/gky797

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 9. — BCR-ABL1 induces genomic deletions associated with replication changes. (A, B) 2D histograms of OK-seq coverage (log2(cRPKG)) in TF1-BCRABL-1M versus TF1-GFP (A) and TF1-BCRABL-6M vs. TF1-BCRABL-1M (B). Stable and unstable diploid and triploid regions are outlined. Normalized histogram values are colour-coded from blue (0.0) to red (3.2) using the colour bar on the right. (C, D) Cdfs of Step 1 (C) and Step 2 (D) RFD changes in indicated regions of panels A and B. Regions where cdfs separate in panel D are enlarged (insets).