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. 2018 Oct 19;11(10):2041. doi: 10.3390/ma11102041

Figure 8.

Figure 8

In vivo therapeutic efficacy of DESN under low-energy ultrasound irradiation: (a) Time-dependent tumor growth curves (n = 5, mean ± SD) after different treatments (control, 5 mg/kg DESN + LEUS, 10 mg/kg DESN + LEUS); (b) Time-dependent body-weight curves of nude mice after different treatments. Inset: tumor weights of mice 13 days after the treatments. Valued are means ± s. e. m. (n = 5 mice per group); (c) The images of tumor volume for nude mice with 4T1 cancer cells treated with blank control i, DESN (5 mg/kg) + LEUS ii, and DESN (10mg/kg) + LEUS iii and (d) Nude mice images of mice treated with one blank control, ii DESN (5 mg/kg) + LEUS, and iii DESN (10 mg/kg) + LEUS. The therapeutic efficacy of DESN under LEUS was obvious. As the concentration of DESN increased, the growth of the tumor was more prominent.