5-FU	Fluorouracil
AF6	Afadin
Akt1	RAC-alpha protein serine/threonine kinase
aPKCζ	Atypical protein kinase C zeta
Arap3	Arf-GAP with Rho-domain, ANK repeat and PH domain-containing protein 3
BCR	B cell antigen receptor
B-Raf	B-Raf proto-oncogene protein serine/threonine kinase, MAPKKK
C3G	Rap guanine nucleotide exchange factor 1
Ca2+	Calcium ion
CAAX	Cys-aliphatic residue-aliphatic residue-X
CAD	Cadherin 1, type 1, E-cadherin
CalDAG-GEF	Calcium/diacylglycerol guanine nucleotide exchange factor
cAMP	3’,5’ cyclic adenosine monophosphate
CAMs	Cellular adhesion molecules
Cdc42	Cell division control protein 42
CD-GEFII	Ras guanyl-releasing protein 2
CD-GEFIII	Ras guanyl-releasing protein 3
CFC	Cardio-Facio-Cutaneous syndrome
CLM	Chronic myelogenous leukemia
CS	Costello syndrome
C3G	Rap guanine nucleotide exchange factor 1
DAG	Diacylglycerol
DOCK4	Dedicator of cytokinesis protein 4
E6TP1	Signal-induced proliferation-associated 1 like protein 1
eIF3-F	Eukaryotic translation initiation factor 3 subunit F
EMT	Epithelial-mesenchymal transition
ERK1/2	Extracellular signal-regulated kinase 1/2, MAPK
F-actin	Filamentous actin
FOXO1	Forkhead box protein O1
FOXO3	Forkhead box protein O3
FPP	Farnesyl pyrophosphate
FRG	Ferm, RhoGEF and pleckstrin domain protein 2
FTase	Farnesyl transferase
GAPs	GTPase-activating proteins
G-CSF	Granulocyte colony stimulating agent
GEFs	Guanine nucleotide exchange factors
GGPP	Geranylgeranyl diphosphate
GGTase I	Geranylgeranyl transferase-1
GGTase II	Rab geranylgeranyl transferase, geranylgeranyl transferase-2
GM-CSF	High-affinity receptor for human granulocyte/macrophage colony-stimulating factor
GPCRs	G protein-coupled receptors, serpentine receptors
GTPase	Guanosine triphosphatase
HMG-CoAR	3-hydroxy-3-methylglutaryl coenzyme A reductase
ICAM-1	Intercellular adhesion molecule 1
ICMT	Isoprenylcysteine carboxyl methyltransferase
IGF-1	Insulin like growth factor
JAM-A	Junctional adhesion molecule-A
JNK	C-Jun N-terminal kinase
KDM6A	(K)-specific demethylase 6A
KMT2D	Lysine-specific methyltransferase 2D
Krit	Krev interaction trapped protein 1
KS	Kabuki syndrome
KSR	Kinase Suppressor of Ras
LFA-1	Lymphocyte function-associated antigen 1
LS	Legius syndrome
MAFbx	Muscle-specific F-box
MAPK	Mitogen-activated protein kinase
MDCK-f3	Mesenchymal Ras-transformed Madin-Darby canine kidney cells
MEK	Mitogen-activated protein kinase, MAPKK
MEK3,6	Mitogen-activated protein kinase 3/6, MAPKK
MET	Mesenchymal-epithelial transition
miR-203	Short non-coding RNA molecule
mTORC1	Mammalian target of rapamycin complex 1
NF1	Neurofibromatosis type 1
NO	Nitric oxide
Nox2	NADH oxidase 2
NS	Noonan syndrome
NSML	Noonan syndrome with multiple lentigins syndrome
p120ctn	Catenin (cadherin-associated protein), delta 1
p38MAPK	P38 MAP kinase
PAR3	Partitioning defective protein 3
PAR6	Partitioning defective protein 6
PECAM-1	Platelet endothelial cell adhesion molecule—also known as CD31—cluster of differentiation 31
PI3K	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
PKA	Protein kinase A
PKD1	Protein kinase D1
PLC	Phosphatidylinositol phospholipase C
PLC-β	Phospholipase C beta
PLC-γ	Phospholipase C gamma
PDZ-GEF	Rap guanine nucleotide exchange factor 2
Rac1/RAC	Rac1-Ras-related C3 botulinum toxin substrate 1
Raf-1	B-Raf proto-oncogene protein serine/threonine kinase, MAPKKK
RapL	Ras associated domain-containing protein 5
RapGAP1	Rap1 GTPase activating protein 1
Repac-RAPGEF5	Rap guanine nucleotide exchange factor 5
RGS14	Regulator of G-protein signaling 14
RIAM	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein
Rho	Ras homolog gene family, member A
Spa1	Signal-induced proliferation-associated gene 1
Spa-L2	Signal-induced proliferation-associated 1 like protein 2
Spa-L3	Signal-induced proliferation-associated 1 like protein 3
Src	Sarcoma family protein tyrosine kinases
TEM	Transendothelial migration
THP-1	Human monocytic cell line 1
TIAM	T-lymphoma invasion and metastasis-inducing protein 1
TLN	Talin
TLRs	Toll-Like Receptors
TPA	12-O-tetradecanoylphorbol 13-acetate
TSC	Tuberous sclerosis
TSC1-TSC2	Hamartin-tuberin complex
TSH	Thyrotropin
VASP	Vasodilator-stimulated phosphoprotein
Vav2	Vav guanine nucleotide exchange factor 2
VCAM-1	Vascular cell adhesion protein 1
α4β1 (VLA-4)	Very late antigen-4
β-cat	Catenin beta 1